Seriously all you need to scale to infinity with Yuber. get 5+ charges on Ice Shield, and the ability to get them all back with tranquility - then Scorch for massive damage.
There is no interaction at all with the game, meaning it cannot stop you from building infinite barrier, while being invincible half the time.
*Optional*
Any CD on Tranquility will make the build more invincible and spam faster.
Any %damage buff on ice shield like Essence of Predation (also giving stats) or Divine Faith is by far the best way to speed up boss clears (you will kill lvl20+ bosses in under a second)
With Essence of Predation for AP the game becomes a literal joke, and you can sleep through whatever is thrown at you. Sleep more that is.
Essence of Wealth can obviously accelerate the process of becoming OP.